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Research Project Title and Description |
Start Date |
Finish Date |
Principal Investigator |
Supervisor/Co-worker |
Status |
Publication Link
(for list go
here) |
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[New]
A pooled analysis of DT scores
and definition of mild, moderate and severe distress
This is pooled analysis of
all DT studies in an attempt to better define cut-offs and thresholds
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January 2010 |
November 2010 |
AJ Mitchell |
TBC
|
Analysis |
Submitted for IPOS10 |
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[New]
Predictors of clinician
willingness to offer psychological care
This is an interesting
project looking at what factors influence cancer nurses' willingness to
offer psychological intervention to patients with cancer
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January 2010 |
November 2010 |
AJ Mitchell |
Paul Symonds
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Analysis |
Submitted for IPOS10 |
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[New]
Implementation of randomized
screening and treatment intervention in Leicester Radiotherapy -
SCREEN PHASE III
This is the end step in our
screening programme designed to combine a screening tool with our in house
PACT self-help intervention
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January 2010 |
February 2011 |
Sue Todd |
Paul Symonds
AJ Mitchell |
Pre-recruitment |
None |
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Detection of Distress vs Anger
vs Anxiety vs Depression by Clinicial Nurse Specialists in Cancer Care
This is a primary data
collection project looking at nursing recognition of emotional
complication of cancer
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August 2009 |
February 2010 |
N Hussain |
AJ Mitchell |
Completed |
Submitted for IPOS10 & Psycho-oncology |
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[New]
Contribution of physical
symptoms to the emotional complications of cancer
This is a primary data
project and literature review
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August 2009 |
July 2010 |
F Noushad |
AJ Mitchell |
Completed |
Submitted for IPOS10 |
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Implementation of ET based
screening in Leicester Chemotherapy -
SCREEN PHASE II
This is the middle step in
our screening programme designed around the Emotion Thermometers and
focussing on chemotherapy attendees
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February 2009 |
February 2010 |
AJ Mitchell |
Paul Symonds |
Completed |
Submitted for IPOS10 |
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Meta-Analysis of Case-finding
tools for Cancer related Depression
This is a systematic
review and meta-analysis of
the unassisted diagnostic accuracy of the oncologists.
Literature search underway |
August 2009 |
November 2009 |
AJ Mitchell |
Nick Meader |
Completed |
Submitted for IPOS10 |
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Accuracy of Oncologists in Detecting Depression
This is a systematic
review/pooled analysis of
the unassisted diagnostic accuracy of the oncologists.
Literature search underway |
January 2009 |
Extended to Oct 2010 |
AJ Mitchell |
Paul Symonds |
Live (data) |
Presentation delayed |
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Hospital Anxiety and Depression Scale in Cancer: Meta-analysis
This is a meta-analysis of
the diagnostic accuracy of the HADS scale in cancer and palliative care.
Project completed. |
September 2008 |
March 2009 |
AJ Mitchell |
AJ Mitchell |
Completed |
Published in J Aff Disorder (2010) online
first |
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Coping and Adaptation to
Cancer in an Ethnically Diverse Population
In 2007 we received funding
(from Hope against Cancer) to examine the predictors of denial, and also
correlates of trust and therapeutic alliance in cancer patients in
Leicester. We plan to test two hypotheses. Hypothesis 1. Temporal
Characteristics of Denial Will develop Differently in British South Asian
and British White Patients. Hypothesis 2. A difference in the
understanding of the concept of cancer will be maintained in Leicester
British South Asian and British White Cancer Patients at Nine Months. The
study will taken 3 years to complete, beginning January 2008.
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January 2008 |
January 2011 |
Karen Lord |
Paul Symonds
AJ Mitchell |
Live (analysis) |
Early data submitted for IPOS10 |
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Network wide implementation of
DT based screening in Leicester Northampton and Kettering -
SCREEN PHASE I
We have sought agreement on
network wide implementation of a simple screening programme for distress
based on the distress thermometer. In a pilot study, patients on 3 sites
will be screened and compared with the clinicians’ global clinical
impression. We hope to collect 250 responses in the first six months.
|
March 2008 |
March 2009 |
AJ Mitchell |
Reports to LNR board |
Completed |
Presented at IPOS09 |
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Simple Screening Methods to
Detect Depression in cancer Care: An Updated Meta-Analysis
In 2007 a pooled analysis
found 8 analyses of verbal methods to detect depression (Mitchell; JCO
2007 25: 4670-4681). We are now updating this with new data on verbal and
written simple questions (such as the PHQ2) and a comparison against the
HADS. We hope to produce the first meta-analytical summary of accuracy of
the HADS in cancer settings in summer 2008.
|
Sept 2007 |
September 2008 |
AJ Mitchell |
AJ Mitchell |
Completed |
Published British Journal of Cancer (2008) 98,
1934-1943
http://www.nature.com/bjc/journal/
v98/n12/abs/6604396a.html |
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Is Desire for Help A Useful
Outcome in Psychosocial Oncology?
Despite a high rate of
psychosocial distress, depression and anxiety not all patients want
professional help. Recently, Graves and colleagues (Lung Cancer 2007; 55
(2): 215-224) found that only 21% of unselected patients and 29% of those
rated as distressed on the distress thermometer wanted help. We are
currently conducting a study to examine who does and does not want help
and how this relates to underlying distress
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March 2007 |
September 2008 |
Elena Baker-Glenn |
AJ Mitchell |
Completed |
Published in Psycho-oncology |
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Validation of the new Emotion
Thermometer (ET) Tool for Detecting Distress and Depression in Cancer
Description: We developed a
new 5 area visual analogue scale to attempt to detect distress in a way
that would be acceptable to staff and patients. 130 patients completed
questionnaires at baseline and 87 were followed at one month, to give a
total sample of 217 with complete data. Accuracy of the PHQ2 question 1
(interest), PHQ2 question 2 (depression), PHQ Q1 OR Q2, PHQ9, HADS-T,
HADS-D as well as the DT and Depression Thermometers were compared.
|
March 2007 |
September 2008 |
Elena Baker-Glenn |
AJ Mitchell
P Symonds |
Completed |
Published in Psycho-oncology |
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Coping and Adaptation to
Cancer in an Ethnically Diverse Population - Cross-Sectional Study
In 2007 we received funding
(from Hope against Cancer) to examine the predictors of denial, and also
correlates of trust and therapeutic alliance in cancer patients in
Leicester. We plan to test two hypotheses. Hypothesis 1. Temporal
Characteristics of Denial Will develop Differently in British South Asian
and British White Patients. Hypothesis 2. A difference in the
understanding of the concept of cancer will be maintained in Leicester
British South Asian and British White Cancer Patients at Nine Months. The
study will taken 3 years to complete, beginning January 2008.
|
January 2008 |
January 2011 |
Raj Roy |
Paul Symonds |
Complete |
Roy R, Symonds RP, Kumar DM, Ibrahim K,
Mitchell AJ, Fallowfield L. The use of denial in an ethnically
diverse British cancer population. A
cross-sectional study. Br J Cancer 2005 92(8): 1393-1397
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Acceptability of Common
Screening Methods Used to Detect Distress and Related Mood Disorders -
Preferences of Cancer Specialists and Non-Specialists.
A new questionnaire of
clinicians' attitudes and practices in relation to screening for mood
disorder was distributed to 300 cancer professionals (specialists and
non-specialists) working across the UK. From 226 (75.3%) health
professionals working in cancer care who responded, approximately
two-thirds always or regularly attempted to detect mood disorder during
consultations but a substantial minority relied on patients spontaneously
mentioning an emotional issue. The highest rate of routine questioning was
performed by clinicians working in palliative medicine (76.3%) as well as
nurse specialists working in all areas (72%).
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Sept 2006 |
September 2007 |
Stephen Kaar |
AJ Mitchell |
Completed |
Psycho-oncology 2007 V17:226 |
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Ultra-short screening
methods to detection distress in cancer settings - meta-analysis of the DT
and related methods.
Ultra-short screening tools
involving fewer than five questions have been recommended as a simple
method of detecting distress, anxiety, or depression in cancer settings.
Such methods have practical appeal, but their diagnostic accuracy is
unclear. A literature search limited to diagnostic validity studies of
ultra-short screening in cancer settings identified 38 analyses, including
19 assessing the Distress Thermometer alone, involving a total of 6,414
unique patients. The pooled ability of ultra-short methods to detect
depression was given by a sensitivity of 78.4%, a specificity of 66.8%, a
positive predictive value (PPV) of 34.2%, and a negative predictive value
(NPV) of 93.4%. Thus these tools were very good at excluding possible
cases of depression but poor at confirming a suspected diagnosis. The
pooled ability of ultra-short methods to detect anxiety was given by a
sensitivity of 77.3% and a specificity of 56.6% (PPV, 55.2%; NPV, 80.25%)
and for distress a sensitivity of 78.3% and a specificity of 66.5% (PPV,
59.7%; NPV, of 82.8%).
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March 2006 |
September 2007 |
AJ Mitchell |
AJ Mitchell |
Completed |
Journal
of Clinical Oncology 2007 Oct 10;25(29):4670-81. |
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Deleted to archive |
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